The DC-8 Meteorological and Navigation Data CPEX-AW dataset is a subset of airborne measurements that include GPS positioning and trajectory data, aircraft orientation, and atmospheric state measurements of temperature, pressure, water vapor, and horizontal winds. These measurements were taken from the NASA DC-8 aircraft during the Convective Processes Experiment – Aerosols & Winds (CPEX-AW) field campaign. CPEX-AW was a joint effort between the US National Aeronautics and Space Administration (NASA) and the European Space Agency (ESA) with the primary goal of conducting a post-launch calibration and validation activities of the Atmospheric Dynamics Mission-Aeolus (ADM-AEOLUS) Earth observation wind Lidar satellite in St. Croix, U.S. Virgin Islands. Data are available from August 17, 2021 through September 4, 2021 in ASCII format.