The DC-8 Meteorological and Navigation Data CPEX-CV dataset is a subset of airborne measurements that include GPS positioning and trajectory data, aircraft orientation, and atmospheric state measurements of temperature, pressure, water vapor, and horizontal winds. These data were gathered during the Convective Processes Experiment – Cabo Verde (CPEX-CV) field campaign. The NASA CPEX-CV field campaign was based out of Sal Island, Cabo Verde from August through September 2022. The campaign is a continuation of CPEX – Aerosols and Winds (CPEX-AW) and will be conducted aboard the NASA DC-8 aircraft equipped with remote sensors and dropsonde-launch capability that will allow for the measurement of tropospheric aerosols, winds, temperature, water vapor, and precipitation. The overarching CPEX-CV goal was to investigate atmospheric dynamics, marine boundary layer properties, convection, the dust-laden Saharan Air Layer, and their interactions across various spatial scales to improve understanding and predictability of process-level lifecycles in the data-sparse tropical East Atlantic region. These data files are available from September 2, 2022, through October 3, 2022, in ASCII format.