The SPURS (Salinity Processes in the Upper Ocean Regional Study) project is a NASA-funded oceanographic process study and associated field program that aim to elucidate key mechanisms responsible for near-surface salinity variations in the oceans. The project is comprised of two field campaigns and a series of cruises in regions of the Atlantic and Pacific Oceans exhibiting salinity extremes. SPURS employs a suite of state-of-the-art in-situ sampling technologies that, combined with remotely sensed salinity fields from the Aquarius/SAC-D, SMAP and SMOS satellites, provide a detailed characterization of salinity structure over a continuum of spatio-temporal scales. The SPURS-2 campaign involved two month-long cruises by the R/V Revelle in August 2016 and October 2017 combined with complementary sampling on a more continuous basis over this period by the schooner Lady Amber. Focused around a central mooring located near 10N,125W, the objective of SPURS-2 was to study the dynamics of the rainfall-dominated surface ocean at the western edge of the eastern Pacific fresh pool subject to high seasonal variability and strong zonal flows associated with the North Equatorial Current and Countercurrent. Underway surface profiling systems (USPS) are automated measurement systems coupled to a research vessels water intake and GPS systems. They provide continuous, along-track surface temperature and salinity measurements at depths of 2, 3 and 5 m using through-hull ports in the bow of the ship. Both SPURS-2 cruises had USPS and associated thermosalinograph (TSG) instrumentation, with measurements calibrated against onboard salinometers. There is one USPS netCDF containing the complete series for each of the 2 cruises.