This dataset provides turbidity measurements with co-located water and air pressure and temperature measurements in portions of the Mississippi River Delta, coastal Louisiana, US. Data were collected at five sites in Atchafalaya River Basin in Spring (2021-03-24 to 2021-04-02) and eight sites in the Atchafalaya River and Terrebonne Basins in Fall 2021 (2021-08-16 to 2021-08-27). In order to sample various hydrodynamic conditions, sensors were deployed at island edges, island interior, and other portions of wetlands. Sensors recorded turbidity, absolute pressure, and temperature. The Delta-X mission is a 5-year NASA Earth Venture Suborbital-3 mission to study the Mississippi River Delta in the United States, which is growing and sinking in different areas. River deltas and their wetlands are drowning as a result of sea level rise and reduced sediment inputs. The Delta-X mission will determine which parts will survive and continue to grow, and which parts will be lost. Delta-X begins with airborne and in situ data acquisition and carries through data analysis, model integration, and validation to predict the extent and spatial patterns of future deltaic land loss or gain. The data are provided in comma-separated values (CSV) files.