The Daily 8-Hour Maximum and Annual O3 Concentrations for the Contiguous United States, 1-km Grids, v1 (2000 - 2016) data set contains estimates of ozone concentrations at a high resolution in space (1 km x 1 km grid cells) and time (daily) for the years 2000 to 2016. These predictions incorporated various predictor variables such as Ozone (O3) ground measurements from the U.S. Environmental Protection Agency (EPA) Air Quality System (AQS) monitoring data, land-use variables, meteorological variables, chemical transport models and remote sensing data, along with other data sources. After imputing missing data with machine learning algorithms, a geographically weighted ensemble model was applied that combined estimates from three types of machine learners (neural network, random forest, and gradient boosting). The annual predictions were computed by averaging the daily 8-hour maximum predictions in each year for each grid cell. The results demonstrate high overall model performance with a cross-validated R-squared value against daily observations of 0.90 and 0.86 for annual averages.